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10 Oct 2008
A new HDAC inhibitor
Scripts Research Institute has developed a new HDAC inhibitor that partially restores normal gene transcription and improves movement and brain volume in the HD mice. 6 Oct 2008
Cytochrome c release as a therapeutic target
Methazolamide delays disease onset and significantly prolongs survival in the R6/2 mouse model of HD. 21 Sep 2008
Why did CEP-1347 fail in the Parkinson′s trial?
The possible reasons for the failure of CEP-1347 as a PD treatments are reviewed. 21 Sep 2008
mRNA levels of BDNF in rodent models of HD
mRNA levels of BDNF decline with disease progression in rodent models of HD and are restored to normal levels by CEP-1347. 19 Sep 2008
CEP-1347 restores BDNF expression in the R6/2 mice
CEP-1347 may be a candidate for the research pipeline of potential HD treatments. 17 Sep 2008
A strict Mediterranean diet can help reduce deaths from major chronic diseases
Sticking to a full Mediterranean diet provides substantial protection against major chronic diseases. 17 Aug 2008
FDA approves tetrabenazine
The FDA approves the first drug specifically for Huntington 17 Aug 2008
Activation of the immune system in HD
Researchers find indicators of an activated immune system in the blood and the brains of HD patients and HD mice. 29 Jul 2008
Ritalin and JHD - a case study
A child with JHD was diagnosed as ADHD and given Ritalin which exacerbated HD symptoms. 21 Jul 2008
Class of antibiotics enhances RNAi
Antibiotics known as fluoroquinolones can make RNA interference more effective. All Updates for Home |
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