Welcome to the HDlighthouse! Getting started.
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New to the Huntington's Disease Lighthouse? Welcome to the HDlighthouse! Getting started.
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Cellular AggregatesThis page focuses on research on formation of aggregates caused by HD. |
Research related to the role Brain Derived Neurotrophic Factor has on the pathology of HD in the brain
Research related HD and it's general affect on the brain
Learn more about the clinical trial process, trials that have been conducted and those that are underway.
Research related to drugs and supplements that may delay onset and slow progression of Huntington's Disease.
Research focusing on gene therapy.
Research focusing on gene transcription.
General research related to HD
Research studying the genetics of Huntington's Disease
Research studying the Immune System and it's effect on the progression of HD
Research studying the brain tissue and research related to stem cells
22 Dec 2009
Synaptic activity, aggregation, and memantine
Normal synaptic activity is neuroprotective, that extrasynaptic activity is toxic, and that memantine will suppress the later while leaving the former unaffected. 8 Apr 2009
Toxic HD protein fragments
Research continues to support the toxic fragment hypothesis. 14 Jun 2008
The HD protein is toxic in the cytoplasm
An intracellular antibody which targets the HD protein in the cytoplasm of the cell ameliorates motor symptoms in the HD mice. 12 Jan 2005
Inhibiting the HD protein aggregates
Researchers have discovered four compounds which can inhibit huntingtin's aggregation in cell models and a fruitfly model of HD. ...
All Updates for Cellular Aggregate Formation |
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