HDL Updates

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Tapestry Pharmaceuticals to invest in oligonucleotide research as a potential treatment for HD
Dr. Eric Kmiec and colleagues at the University of Delaware and Massachusetts General Hospital have been able to inhibit HD ...
Marsha L. Miller, Ph.D.
Posted to HDL: 03 Oct 2004

A Major Breakthrough in RNA Interference Therapy
RNA interference therapy has become the most promising hope for a real cure for Huntington's Disease. HD researchers called ...
Marsha Miller, Ph.D.
Posted to HDL: 06 Jul 2004

Virus Delivers Potential Huntington Treatment
Ciliary neurotrophic factor (CNTF) has been shown to prevent behavioral deficits and striatal degeneration in neurotoxic models of Huntington's disease ...
Jerry Lampson
Posted to HDL: 31 Dec 2003

Gene Therapy World's First to Market
The world's first commercially available gene therapy medication will soon be treating head and neck cancer in China. ...
Jerry Lampson
Posted to HDL: 21 Nov 2003

The Revolution of Short RNAs and Huntington's
Sharp, an expert in RNA splicing, discussed the discovery of short RNAs and their implications for wide-ranged biology. He spoke ...
Jerry Lampson
Posted to HDL: 04 Nov 2003

Parkinson's Disease Gene Therapy Trial
Researchers slipped billions of copies of a gene into the brain of a Parkinson's disease patient Monday, marking the first ...
Jerry Lampson
Posted to HDL: 19 Aug 2003

****Clinical Trial For ALS Gene Therapy
Gene therapy has delayed symptoms and almost doubled life expectancy in mice with the equivalent of Lou Gehrig's disease, a ...
Jerry Lampson
Posted to HDL: 09 Aug 2003

NAPRO EXTENDS LIFE OF BRAIN CELLS
NaPro announces results of a recent study using its proprietary technology in a novel approach to treating Huntington’s disease. These ...
Jerry Lampson
Posted to HDL: 09 Jun 2003

**** Huntington's Disease Treatment
The company designed a strand of genetic material to block a patient's own DNA from coding for a particular protein. ...
Jerry Lampson
Posted to HDL: 09 Jun 2003

HD Rats Protected by Gene Therapy
These data indicate that the viral-mediated gene transfer of GDNF into the striatum provides neuroanatomical and behavioral protection in a ...
Jerry Lampson
Posted to HDL: 05 Jun 2003

DISEASE-CAUSING GENE SILENCED
Researchers recently showed it is possible to silence a mutant gene without affecting the expression of a normal gene. In ...
Jerry Lampson
Posted to HDL: 30 May 2003

Nanodevices To Fix Defective Genes
Nanotechnology may help overcome current limitations of gene therapy. Scientists from Northwestern University and Argonne National Laboratory have created a ...
Jerry Lampson
Posted to HDL: 20 Apr 2003

***Gene Replacement Success
Scientists from the University of Texas Medical Branch at Galveston and the University of Florida have used gene therapy to ...
Jerry Lampson
Posted to HDL: 02 Apr 2003

Switching Off Huntington's Disease
Using gene therapy to switch off genes instead of adding new ones could slow down or prevent the fatal brain ...
Original story by Bob Holmes, Banff 10:32 13 March 03
Posted to HDL: 13 Mar 2003

50 years of DNA
Fifty years ago Friday, James Watson and Francis Crick discovered the structure of DNA, a discovery that transformed molecular biology. ...
Jerry Lampson
Posted to HDL: 28 Feb 2003

Stem Cells From Blood
The powerful, scarce and flexible forms of stem cells needed for medical research and treatment may now be both plentiful ...
Jerry Lampson
Posted to HDL: 25 Feb 2003

Patent Promises To Speed Gene Therapy
Mayo Clinic researchers have received a U.S. patent for their invention of a new way to use a synthetic molecule ...
Jerry Lampson
Posted to HDL: 21 Feb 2003

Petunias and Curing HD
RNA interference (RNAi), is just one of a whole series of newly recognized phenomena that have stolen some of the ...
Jerry Lampson
Posted to HDL: 18 Feb 2003

Gene Silencing
One of the most important breakthroughs in modern molecular biology is the discovery that double-stranded RNA can quash the activity ...
Jerry Lampson
Posted to HDL: 12 Feb 2003

Gene Knockdown Demonstrated In Mice
A new study published in the February issue of Nature Structural Biology reports the creation of transgenic mice in which ...
Jerry Lampson
Posted to HDL: 20 Jan 2003
Updated: 01 Feb 2003

Gene Therapy Trials Suspended
U.S. officials are suspending 27 more gene therapy studies while they investigate a possible serious risk: A second European toddler ...
Adapted by Jerry Lampson
Posted to HDL: 15 Jan 2003

Researchers Develop Novel Method to Silence Genes in Mice
University of Iowa scientists have for the first time combined gene therapy strategies and a process that interferes with gene ...
University of Iowa press relelease 16-Sep-2002
Posted to HDL: 16 Sep 2002

Novel 'Antisense' Technology Targets Thrush
Chemists have invented a new type of 'antisense' technology that provides a simpler and less expensive method to knock out ...
Adapted from University of Rochester Medical Center press release 14-Sep-02
Posted to HDL: 16 Sep 2002

Regulatable gene therapy
Artificial transcription factors can be up- or down-regulate a given target gene.... ...
Martina Habeck, Drug Discovery Today
Posted to HDL: 01 Aug 2002

Virus Delivers HD Neuroprotection
Virus delivers neuroprotection to huntington`s disease rat models... ...

Posted to HDL: 02 Jun 2002

Virus Delivers HD Neuroprotection
Virus delivers neuroprotection to huntington`s disease rat models. ...

Posted to HDL: 02 Jun 2002

Cow Wart Virus Delivers Genes
Researchers have been looking for better ways to fix genes. It is a fascinating development that researchers in Estonia exploiting ...
Adapted from BioMed Central and Freedom of Information
Posted to HDL: 14 May 2002

Gene Therapy Success
Gene Therapy Reverses Brain Function Impairment in Animal Model... ...
University of Iowa Health Center press release16-Apr-02
Posted to HDL: 16 Apr 2002

Gene Therapy Progress
Hemophilia trials, other studies may herald successful gene therapies for human diseases.... ...
Childrens Hospital of Philadelphia
Posted to HDL: 15 Feb 2002