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  HD Lighthouse Editors Comment: Tauroursodeoxycholic Acid (TUDCA) treats HD model mice. It is likely that TUDCA will treat HD in humans. TUDCA is being investigated for the treatment of human conditions. --Jerry
Posted to HDLighthouse:
11-Oct-01
HDL Update: Tauroursodeoxycholic Acid FDA Grants


Grants Awarded by the Office of Orphan Products Development (OOPD) Grant Program

James E. Heubi, M.D.
Pediatric Gastroenterology, Hepatology and Nutrition
Phone: 513-636-8046
Fax: 513-636-4695
E-mail: sjames.heubi@chmcc.org

Title: Tauroursodeoxycholic Acid Prophylaxis for TPN Cholestasis
$99,873/$300,439
Principal Investigator: Dr. James Heubi
Insititution: Children's Hospital Research Foundation
City and State: Cincinnati, OH

Title: Tauroursodeoxycholic Acid for Treatment of Hepatobiliary Disease in Cystic Fibrosis
Principal Investigator: Dr. Kenneth Setchell
Insititution: Children's Hospital Research Foundation
City and State: Cincinnati, OH s

For more information see:
http://www.fda.gov/orphan/grants/info.htm
http://www.fda.gov/
http://www.cincinnatichildrens.org/chrf/

Source: HDL 03-Oct-01

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Ursodiol Treatment Now
A generic prescription drug treats Huntington's Disease... ...
Jerry Lampson, HDL Editor
Posted to HDL: 13 Sep 2002

Absorption
Oral UDCA is preferred to injectable TUDCA for the treatment of HD. UDCA is at a pharmacy close to you.... ...
Adapted from Eur J Clin Invest 2002 Aug;32(8):575-80 Rudolph G et al. by Jerry Lampson
Posted to HDL: 27 Aug 2002

TUDCA HD Research Progress
This is an update on the -Bile Acid Treats HD- and -TUDCA Dose, Safety- articles. Dirk Keene has kindly responded ...
From Dr. Walter Low's laboratory at the University of Minnesota Medical School
Posted to HDL: 11 Oct 2001

TUDCA HD Research Progress
This is an update on the -Bile Acid Treats HD- and -TUDCA Dose, Safety- articles. Dirk Keene has kindly responded ...
From Dr. Walter Low's laboratory at the University of Minnesota Medical School
Posted to HDL: 11 Oct 2001

TUDCA Trials
Tauroursodeoxycholic Acid (TUDCA) treats HD model mice. It is likely that TUDCA will treat HD in humans. TUDCA is being ...
HDL
Posted to HDL: 03 Oct 2001

Tauroursodeoxycholic Acid Dose, Safety
Bile acid (TUDCA) is used to treat liver disease. TUDCA also treats HD in a rat model of HD.( ref) ...
Adopted from:Dig Dis Sci 1996 Apr;41(4):809-15 Crosignani A, et al
Posted to HDL: 30 Sep 2001
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